Jermuk occupies an area which is historically considered as part of the Vayots Dzor canton of the Syunik province of Greater Armenia. It was first mentioned during the 13th century by historian Stepanos Orbelian in his work History of the Province of Sisakan. The remains of an ancient cyclopean fortress and the ruins of an 8th-century basilica testify that the region around the fountains of Jermuk has been settled long before the 13th century. The area of Jermuk has been ruled by the Siunia dynasty between the 10th and 13th centuries, when Vayots Dzor was part of the Kingdom of Syunik. The princes of Syunik regarded the mineral springs of Jermuk as healing and built several pools filled with it, thereby making the little town their holiday destination. During the Middle Ages, the Silk Road passed through the area of Vayots Dzor, particularly the road that currently links the town of Martuni with Yeghegnadzor to the northwest of Jermuk.